Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.
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چکیده
منابع مشابه
Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.
The CD4 molecule, expressed by T cells restricted by class II major histocompatibility complex (MHC) molecules, is believed to play a role in T-cell activation. We have previously suggested that CD4 interacts with the T-cell receptor for antigen (TCR) and with class II MHC and that this dual interaction stabilizes the bond between the TCR and antigen in association with MHC. To investigate the ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1987
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.84.24.9209